Male puberty is understudied — but when it starts may predict long-term health risks

mental-health

Research into the timing of female puberty has established clear links to long-term health outcomes, but an equivalent research gap exists for males. Early puberty in girls is connected to higher risk for endometriosis, type 2 diabetes, heart disease, breast cancer, depression, eating disorders, uterine fibroids, osteoarthritis, and all-cause mortality. Both early and late puberty—before 8 and after 13 years old—are associated with early menopause and its attendant health risks. Between 1990 and 2016, there were approximately 1.67 times more published research papers on female puberty than male puberty, prompting calls from researchers to rectify this significant gender gap.

Male health researchers argue that better understanding the relationship between puberty timing and disease risk in men could enhance identification and prevention of chronic illnesses. Anders Juul, a professor of pediatric endocrinology at the University of Copenhagen, states that “increased knowledge on factors regulating timing of male puberty may be the key to understanding long-term health in males.” More than half of American male deaths in 2023 were considered premature, with average life expectancy at 75.8 years—6.5 years less than for men from the longest-lived high-income countries. Leading causes include heart disease, cancer, and diabetes—conditions tied to puberty timing.

A 2015 study using data on 500,000 individuals in the UK Biobank found that earlier puberty timing in boys and girls was associated with 48 negative outcomes across cancers, cardio-metabolic, gastrointestinal, musculoskeletal, and neuro-cognitive categories. Other studies associate early puberty in boys with higher risk of heart attack, type 2 diabetes, obesity, depression, and ADHD. A 2024 study found a strong genetic connection between men’s hair color and puberty timing, with adolescents having red, dark brown, or black hair showing “progressively higher” chances of early puberty onset. Late puberty carries distinct health risks including anxiety, panic attacks, depression, asthma, and eczema, though one study found that for every year puberty onset was delayed, it translated to a nine-month longer lifespan in men.


This article is an AI-assisted summary. All facts and figures are drawn from the original report: https://www.statnews.com/2026/06/04/male-puberty-timing-long-term-health-risk-prediction/